Key messages

• The primary indication for an inoconstrictor is a situation where inotropic support is required in the face of low systemic vascular resistance. Inodilators are suited to situations where low cardiac output is associated with high systemic vascular resistance.

• Catecholamines have an agonist effect at the bradrenergic receptor in cardiac muscle, increasing cytoplasmic cAMP which is the fulcrum of all inotropic activity.

• Phosphodiesterase inhibitors exert their inotropic action by inhibiting the breakdown of cAMP by its specific enzyme phosphodiesterase III.

Was this article helpful?

0 0
Sleep Apnea

Sleep Apnea

Have You Been Told Over And Over Again That You Snore A Lot, But You Choose To Ignore It? Have you been experiencing lack of sleep at night and find yourself waking up in the wee hours of the morning to find yourself gasping for air?

Get My Free Ebook

Post a comment