Ketamine

This intravenous or intramuscular anesthetic agent has bronchodilating properties that do not appear to act via the b-adrenergic receptor. There is evidence from animal studies and from case reports in humans that it is a useful bronchodilator. The adult dose ranges from 1 to 2 mg/kg initially, followed by an infusion of 10 to 40 pg/kg/min.

Side-effects include tachycardias, hypertension, hallucinations, and raised intracranial pressure. As with the inhalational agents, this is not a drug for the inexperienced clinician but should be administered by those experienced in its use.

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