Over the last 30 years major advances have been made in transfusion medicine and nowadays virtually all collected blood is separated into its components. There is now the potential for prolonged periods of storage of relatively pure components without functional detriment. Techniques for fractionating plasma have been refined and increasingly sophisticated methods of viral inactivation have been developed in attempts to render all plasma products safe. Advances in molecular technology have resulted in the production of a factor VIII concentrate made by recombinant technology, and there are other recombinant products to follow.

In most hospitals all products described below will be issued to the user by the hospital blood bank, and nowadays it is obligatory that there is adequate documentation detailing what product is given to which patient.

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