Introduction

Occlusion of pulmonary vessels may occur at both macro- and microcirculatory levels, and the disease process may be acute or chronic. Here we focus on the mechanisms, pathophysiology, diagnosis, and management of acute pulmonary microvascular occlusion involving arterioles, capillaries, and venules. This may be present in several diseases commonly encountered in intensive care patients, including acute respiratory insufficiency of different origins, sepsis, and disseminated intravascular coagulation (DIC). Microvascular occlusion due to chronic or idiopathic disease will not be discussed.

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