Introduction

Malaria is the most common life-threatening infection acquired by travelers to tropical countries. Chemoprophylaxis reduces the risk of infection, but does not remove it. All patients who become critically ill within 12 months of returning from a malarious area must have malaria excluded, even if they took chemoprophylaxis. Falciparum malaria has been reported up to a year following return from an endemic area. Malaria should also be considered in fever not due to other causes months or years after traveling to an area where Plasmodium vivax or Plasmodium ovale infections are common, as relapses due to liver hypnozoites can occur long after initial exposure.

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