Introduction

Hemostasis is a remarkable achievement of evolution which reconciles two conflicting requirements, namely that blood should clot extremely rapidly in order to prevent exsanguination and yet preserve liquidity in the circulation. It requires a highly complex, and intricate balance between the vascular endothelium, the coagulation cascade, anticoagulant mechanisms, the fibrinolytic system, platelets, leukocytes, cytokines, and blood flow dynamics.

In the critically ill patient, abnormalities of hemostasis are common and relate to the deregulation of host defense homeostatic mechanisms by trauma, infection, surgery, drugs, cytokines, and instability of the cardiorespiratory axis. Therefore the critically ill patient can present with either bleeding or thrombosis and in some cases with both.

Sleep Apnea

Sleep Apnea

Have You Been Told Over And Over Again That You Snore A Lot, But You Choose To Ignore It? Have you been experiencing lack of sleep at night and find yourself waking up in the wee hours of the morning to find yourself gasping for air?

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