Many patients with SIRS have concurrent infection, which may be causing SIRS or may merely be a coexisting finding. All patients with multisystem involvement following a primary disease must be carefully screened for infection, with attempts made to arrive at a microbiological diagnosis. Appropriate skin and wound swabs, as well as specimens of sputum, urine, blood, and drainage fluid for culture and sensitivity, should be taken in the suspected septic patient. Repeat cultures should be taken during pyrexial episodes.
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