HT3 receptor antagonists

5-HT3 receptor antagonists are expensive compared with other antiemetics but are often effective for otherwise unresponsive nausea and vomiting. They block vagal afferent pathways and 5-HT receptors in the area postrema. Ondansetron, tropisetron, and granisetron are much more active at the 5-HT 3 receptors than at other

5-HT receptors. Their efficacy is similar (Morrow ,.§LqL 1995). They are effective in nausea and vomiting induced by cancer chemotherapy and radiotherapy. For postoperative nausea and vomiting, ondansetron 8 mg is more effective than either metoclopramide 10 mg or droperidol 1.25 mg, all given intravenously. A combination of ondansetron and droperidol can be effective in vomiting after neurosurgery or removal of acoustic neuroma which is difficult to control. The 5-HT 3 receptor antagonists have few side-effects; the most common is headache.

Sleep Apnea

Sleep Apnea

Have You Been Told Over And Over Again That You Snore A Lot, But You Choose To Ignore It? Have you been experiencing lack of sleep at night and find yourself waking up in the wee hours of the morning to find yourself gasping for air?

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