Gammaglutamyl transferase

Gamma-glutamyl transferase is a membrane-bound glycoprotein which is found in cells with a high secretory or absorptive activity, such as the liver, kidney, pancreas, intestine, and prostate. Serum levels of g-glutamyl transferase are high in almost all forms of liver disease, with particularly high levels in intrahepatic biliary obstruction. Ninety per cent of patients with hepatobiliary disease have raised levels of g-glutamyl transferase, but the test has a poor specificity because of the many other conditions that also give raised levels (Table. ...3).

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