Forced diuresis is the administration of high volumes of intravenous fluids alone, or in combination with diuretics, with the goal of enhancing urinary excretion. It is fraught with the potential for complications, including pulmonary and/or cerebral edema, hypokalemia, hypernatremia, and hyponatremia ( GarrettsgniiandGeller... 1990). Furthermore, its efficacy has been demonstrated for only a few toxins (JableS). A urine output of 2 to 4 ml/kg/h is a reasonable goal of therapy.
table 6 Agents susceptible to enhanced elimination by forced diuresis
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