The appropriate treatment of anaphylaxis depends on a number of important factors. The location of the reaction
Although the majority of reactions occur outside the hospital, many progress rapidly. The optimum immediate treatment may vary, particularly if oxygen and intravenous fluid are not available. Epinephrine by intramuscular injection rather than intravenously is effective if given early and is safer than intravenous injection in a patient whose electrocardiograph and blood pressure are not monitored ( Fisher J 99.5).
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