Endothelial cell activation with increased capillary permeability

The etiology of capillary leak leading to peripheral edema and proteinuria associated with acute mountain sickness is elusive. Although some inflammatory mediators (e.g. plasma eicosanoids, serum phospholipid bound arachidonic acid, urinary leukotriene E4 levels) are found to be elevated in patients with acute mountain sickness but without high-altitude pulmonary edema, others (e.g. IL-1-b, IL-2 and its soluble receptors, IL-6, IL-8, tumor necrosis factor-a and its soluble receptor) are not. Thus overall endothelial cell activation seems to be minor, although regional differences cannot be excluded.

Kicking Fear And Anxiety To The Curb

Kicking Fear And Anxiety To The Curb

Kicking Fear And Anxiety To The Curb Can Have Amazing Benefits For Your Life And Success. Learn About Calming Down And Gain Power By Learning Ways To Become Peaceful And Create Amazing Results.

Get My Free Ebook


Post a comment