High-dose aprotinin to prevent postoperative bleeding in cardiopulmonary bypass or to arrest bleeding associated with prolonged extracorporeal circulation requires a loading dose of 2 * 106 kIU (over 20 min) followed by 500 000 kIU/h intravenously. As a polypeptide, aprotinin is not active if given orally.

Low-dose aprotinin to reverse the action of thrombolytics requires a loading dose of 500 000 kIU (over 10 min) followed by 200 000 kIU/h intravenously until bleeding stops.

Sleep Apnea

Sleep Apnea

Have You Been Told Over And Over Again That You Snore A Lot, But You Choose To Ignore It? Have you been experiencing lack of sleep at night and find yourself waking up in the wee hours of the morning to find yourself gasping for air?

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