Stool contains 50 to100 mmol/l of potassium. Diarrhea is usually associated with significant losses of bicarbonate and hence a metabolic acidosis. This may be further increased by the effects of hypovolemia; the consequent shift of potassium from cells may mask the true extent of potassium depletion. In certain conditions, such as villous adenomas of the rectum and non-insulin-secreting islet cell tumors, diarrhea may contain high chloride concentrations. In such cases potassium loss occurs without an accompanying acid-base disturbance; hence hypokalemia tends to be more profound for a given whole-body potassium deficit. Laxative abuse similarly produces a profound hypokalemia without alterations in acid-base status. Patients with ureterosigmoidostomies, where urine is allowed to stagnate in the colon, may develop a profound hypokalemic hypochloremic acidosis. Potassium losses are increased in conditions of rapid intestinal transit, small bowel fistulas, intestinal drains, malabsorption, and small bowel bypass.

Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

Get My Free Ebook

Post a comment