Corticosteroids

Chronic inflammation is central to the pathogenesis of asthma, and steroids are the most effective agents in the control of asthma. There are several studies demonstrating the effectiveness of steroids in acute severe asthma. However, the peak response for steroid action does not occur until 6 to 12 h after an intravenous dose; therefore steroids should be given early. Prednisolone 30 to 60 mg orally, hydrocortisone 200 mg intravenously, or methylprednisolone 60 to 125 mg intravenously should be given immediately and continued every 6 h during the initial 24 to 48 h of treatment depending on the patient's condition. Intravenous steroids should be continued until the life-threatening phase is considered to be over and then changed to decreasing oral doses.

Coping with Asthma

Coping with Asthma

If you suffer with asthma, you will no doubt be familiar with the uncomfortable sensations as your bronchial tubes begin to narrow and your muscles around them start to tighten. A sticky mucus known as phlegm begins to produce and increase within your bronchial tubes and you begin to wheeze, cough and struggle to breathe.

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