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Bernard, G.R., et al. (1995). Quantification of organ failure for clinical trials and clinical practice. American Journal of Respiratory and Critical Care Medicine, 151, A323 (abstract). Knaus, W.A., Draper, E.A., Wagner, D.P., and Zimmerman, J.E. (1985). APACHE II: a severity of disease classification system. Critical Care Medicine, 13, 818-29.

Le Gall, J., Lemeshow, S., and Saulnier, F. (1993). A new simplified acute physiology score (SAPS II) based on a European/North American multicenter study. Journal of the American Medical Association, 270, 2957-63.

Le Gall, J., Lemeshow, S., and Saulnier, F. (1993). A new simplified acute physiology score (SAPS II) based on a European/North American multicenter study. Journal of the American Medical Association, 270, 2957-63.

Berlin.

Vincent, J.-L., et al. (1997). The SOFA (Sepsis-Related Organ Failure Assessment) score to describe organ dysfunction/failure. Intensive Care Medicine, 22, 707-10.

Berlin.

Vincent, J.-L., et al. (1997). The SOFA (Sepsis-Related Organ Failure Assessment) score to describe organ dysfunction/failure. Intensive Care Medicine, 22, 707-10.

Introduction General.thera.pies

Removal. .ofaseptic .focus

Resuscitation

Organ-directed.. therapy

Lung

Heart

Kidneys

Coagulation

Brain

Liver

Conclusion

Bibliography

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