Beta-blockers work by reducing heart rate and the inotropic effect of sympathetic stimulation, thereby decreasing myocardial oxygen demand. There is little to choose between the myriad of b-blockers available, although the more selective b rblockers reputedly have a better side-effect profile. Recent studies have demonstrated a beneficial effect of perioperative b-blockade in patients known to have ischemic heart disease undergoing non-cardiac surgery. A reduction in both acute ischemic episodes and death at 1 year was noted. Heart failure and asthma remain contraindications, but peripheral vascular disease will be of less consequence in these circumstances, at least for the immediate perioperative period.

Your Heart and Nutrition

Your Heart and Nutrition

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