Apparent ('stress') polycythemia (P.e.ais.on,...1991.) is poorly understood, but the contracted plasma volume may be improved by occasional venesection if the hematocrit exceeds 0.55. Although not proven, it is thought that a change of lifestyle for patients with a contracted plasma volume may be beneficial. Therefore such patients should be firmly encouraged to stop both smoking and excessive alcohol intake. Their doctors should avoid prescribing them diuretics, using vasodilators and angiotensin-coverting enzyme inhibitors for antihypertensive and heart failure therapy. The link between stress polycythemia and vascular occlusive diseases is not well understood, and the patient's lifestyle, for example smoking habit, may be more important than a contracted plasma volume and high hematocrit in predisposing to vascular occlusive complications. It is possible that reducing high hematocrit values, for example from 0.55-0.60 to 0.50 or less, may help blood flow and organ perfusion and oxygenation.
G. R. Serjeant
Sickle cell disease
Pathophysiology of sickling
Hemoglobin, levels ..a.nd...tra.nsfusion G,e,n,oty,pe,,,Y,a,ri,at,i,on
Acute.. chest.. syndrome
Pregnancy Pathogenesis Bibliography
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Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...