Some a-receptor blockers are non-selective, such as phentolamine (a 1- and a2-blockade), and some are selective, such as labetalol (a1- and b-blocker). Stimulation of the a1 receptor causes arteriolar and venous constriction, and stimulation of the a 2 receptor causes decreased central sympathetic outflow. This type of drug is particularly useful in the treatment of pheochromocytoma crises, hypertension following intracranial hypertension, and pregnancy-induced hypertension ( Tietjen et al.

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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