Acute chest syndrome Clinical features

There is usually cough, fever, dyspnea, pleuritic pain, and signs of consolidation. There is usually radiological evidence of pulmonary infiltrates, although occasionally a dramatic clinical picture may be associated with minimal radiological change. Some patients exhibit sudden clinical deterioration with rapidly increasing shortage of breath, falling oxygen saturations, and progressive radiological opacity of the lungs. This is usually the picture of acute pulmonary sequestration which has a high mortality without prompt intervention.

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