Accelerated hypertension in pregnancy

Some patients with pregnancy-induced hypertensive disease require ICU admission to control blood pressure. Angiotensin-converting enzyme inhibitors are relatively contraindicated because of the risk of fetal death and nitroprusside because of fear of toxicity. Preferred drugs are labetalol, hydralazine, ketanserin, and calcium blockers. The acute effects of orally administered nifedipine (10 mg) is equivalent to that obtained during continuous infusion of hydralazine (1-3 mg), but the former may have fetal side-effects.

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