There is minimal data on safety and test performance of SLNB during pregnancy. Blue dyes are contraindicated in pregnant patients but radioisotopes are probably safe. Keleher et al. (65) showed that the potentially absorbed radiation dose to the fetus is less than 50mGy threshold absorbed dose for adverse effects to the fetus. Recent reports suggest that SLNB is feasible in pregnant patients without adversely affecting the fetus (66, 67). However, due to small numbers and insufficient follow-up, SLNB cannot be recommended in pregnant women with breast cancer.

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