Lymphangiogenesis And Metastatic Spread Of Breast Cancer

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Mahir A. Al-Rawi and Wen G. Jiang

Metastasis and Angiogenesis Research Group, School of Medicine, Cardiff University, Heath park, Cardiff, CF14 4XN, UK

Abstract: Lymphangiogenesis, the growth and formation of new lymphatic vessels, has been extensively studied in recent years. With the identification of new lymphangiogenic factors and new lymphatic markers, the role of lymphangiogenesis in the progression of breast cancer and in the lymphatic spread of breast cancer cells have been recognized. The current chapter overviews the progress in this area.

Keywords: lymphangiogenesis, breast cancer, VEGF-D, lymphatic markers

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