Conclusion

In breast cancer metastasis the old "seed and soil" hypothesis has started to become elucidated at the molecular level. Cancer cell motility is a necessary "seed" factor, but it is neither a marker for metastatic capability, due to its transient occurrence, nor sufficient on its own. Agents that interfere with the different aspects of cancer cell motility (directional migration, adhesion, and proteolysis) are also candidates for anti-metastatic approaches. Critical interactions with the "soil", as exemplified by the CXCL12/CXCR4 ligand/receptor recognition, are expected to become useful targets for therapy as well. This insight leads to the concept that the cancer cells are not the only targets for treatment, but that "host" cells can also be central players in future anti-metastatic strategies.

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

Get My Free Ebook


Post a comment