Treatment

♦ Small tumours not adjacent to the macula or optic disc—photo-coagulation

♦ Small/moderate tumours—radioactive plaques (iodine, ruthenium plaques-40 Gy)

♦ Large or multiple tumours—external radiotherapy

♦ May need to radiate whole eye (40 Gy, 20 fractions over 4 weeks), try to maintain vision

♦ Occasionally enucleation is required

♦ Tumour is also chemosensitive—platinum

—etoposide —vincristine —doxorubicin —cyclophosphamide

♦ Chemotherapy is useful if tumour has a bad prognosis or in neo-adjuvant setting

♦ Prognosis—90% survival; 80% of patients can have eye preserved

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