The interfraction interval

After a radiation treatment, some of the damage induced is complete but some can be repaired. With a single daily exposure, all or nearly all of the repairable damage is complete before the next treatment is given. If more than one treatment is given during a day, the duration of time between the fractions must be chosen with care to allow for as much repair as possible in the normal tissues. If this is not followed, then there will be an increase in effect, most importantly, in the late reaction of normal tissues.

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