Retinoblastoma

This is a rare intra-ocular tumour arising in young children, usually in the first two years of their life. In a large number of cases the disease is hereditary and often bilateral. As with melanoma, the diagnosis is made by clinical appearance of the lesions. Therefore patients should be managed in combined clinics by ophthalmologists experienced in management of retinoblastoma. Biopsy should not be performed.

Diagnosis may be made by routine screening in those with a family history, by parents noticing their child had a squint or difficulty in visual fixation, or by a white reflex that is indicative of a large intraocular tumour.

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