Radionuclide imaging

Technetium 99m is an ideal diagnostic imaging radionuclide because of its photon energy, short half life of 6 hours, easy production, and ability to attach to a wide variety of radiopharmaceuticals. Some tumours have characteristic properties lending themselves to imaging with such agents. Neuroendocrine and carcinoid tumours concentrate MIBG (meta-iodo-benzyl-guanidine) and thus can be used both for diagnostic and therapeutic purposes. Medullary carcinoma of the thyroid has a high uptake of Technetium 99m DMSA (dimecapto-succinic acid). Cyclotron-generated isotopes used dynamically in PET (positron emission tomography) scanning show potential in certain areas including pancreatic and lung tumours with lymph node spread.

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