Premalignant lesions

Classification should be based on grade of dysplasia, as this has a bearing on prognosis. Most of these lesions are diagnosed on the vocal cords with hoarseness as the symptom. These lesions should be endo-scopically excised (conventional technique or laser) and the specimens should be carefully examined by an experienced pathologist working in close collaboration with the clinician. Radiotherapy may be used for frequently recurring or diffuse lesions. These patients should be carefully followed up as there is not only a risk of development of invasive carcinoma but also a high risk of other primary malignant neoplasms, especially within the upper aero-digestive tract and lungs.

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