Other malignancies

Hodgkin's disease has an increased incidence in HIV-positive patients—5-9 times higher than the general population. It is seen more commonly in patients where transmission of HIV has been by intravenous drug use. The disease is often advanced at the time of presentation. Standard chemotherapy is with ABVD (adriamycin, bleomycin, vinblastine, dacarbazine). The median survival with chemotherapy is 12 months.

Cervical cancer in HIV-positive females became an AIDS-defining diagnosis in 1993. Its increased prevalence may be because both HIV virus and the human papillomavirus (HPV) are sexually transmissible. It is advisable to screen this group more frequently, (every 6-12 months).

Anal cancer is related to both HIV and HPV. It has an increased prevalence in homosexual men practising anal intercourse. However, the risk is higher for those who are also HIV-positive.

Part 5

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