Verrucous carcinoma is a distinct variant of well differentiated squamous cell carcinoma (also named Ackerman's tumour) and is characterized by a verrucous appearance and pushing margins histopathologically, surrounded by a marked inflammatory cell response. Lymphatic spread is rare. Surgical treatment is usually advocated, but a good response to radiotherapy is also reported.
Spindle cell carcinoma is a rare, well-described tumour making up less than 1% of laryngeal malignant tumours. The term 'pseudo-sarcoma' has been used for some of these tumours as the spindle elements were once considered reactive. Immunohistochemical and electron microscopy suggest they are epithelial cells.
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