Localized muscle invasive cancer

Internationally, the commonest pattern of management is radical cystectomy. Prospective trials comparing cystectomy with radical radiotherapy have not show a significant survival difference and the use of radiotherapy in order to seek tumour control with organ conservation is preferred by some clinicians and patients. Improved tumour characterization and other methods of establishing appropriate local treatment should enable better selection of patients for organ conservation with a low risk of local tumour recurrence.

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