Imaging of tumour tissue

Nuclear medicine techniques have a limited role in the characterization of tumours. Modalities such as plain X-ray radiography, ultrasound, CT, and MRI offer superior anatomical detail. The value of tumour-seeking radiopharmaceuticals lies in the capability of distinguishing viable tumour tissue from a specific residual mass after therapy and in convenient screening for additional lesions using whole-body imaging.

Gallium scintigraphy is usually done 48-72 hours after the IV administration of 180 MBq 67Ga-citrate. It is of limited value in the initial staging of Hodgkin's and non-Hodgkin's lymphoma, because of the difficulty of detecting lesions in the abdomen. In patients with Hodgkin's disease and other lymphomas, 67Ga scintigraphy, including SPET is an indicator of residual viable tumour tissue with a better predictive value than CT.

Thallium-201 is widely used for myocardial perfusion imaging. Over the past few years there has been growing interest in the use of 201T1 in oncology. It may be useful in the differentiation between low-and high-grade glial tumours and between tumour recurrence and scar tissue. Thallium-201 scintigraphy can assess residual tumour viability after chemotherapy in bone and soft-tissue sarcomas.

How To Reduce Acne Scarring

How To Reduce Acne Scarring

Acne is a name that is famous in its own right, but for all of the wrong reasons. Most teenagers know, and dread, the very word, as it so prevalently wrecks havoc on their faces throughout their adolescent years.

Get My Free Ebook

Post a comment