Diagnosis and screening

Elevated levels of human chorionic gonadotrophin (HCG) are always seen in choriocarcinoma, but can also be found in normal pregnancy, ectopic pregnancy, in some patients with germ cell tumours, and, occasionally, in patients with non-germ cell tumours. Following diagnosis and evacuation of a hydatidiform mole, patients are followed using serial HCG measurements in blood or urine. Screening allows patients with persistent trophoblastic disease to be detected on the basis of plateauing or rising tumour markers before clinical evidence of a tumour develops.

0 0

Post a comment