Aetiology

The occupational risk of developing bladder cancer for workers in the dye industry was established more than 90 years ago. The association was supported when 2-napthylamine was shown to cause bladder cancer in animals and related carcinogens were associated with increased risk for those working in the aniline dye and the rubber industries. Now, the range of known human bladder carcinogens identifies risks associated not only within these industries mentioned but also for those working in:

♦ Laboratory work

♦ Textile printing

♦ Manufacture of firelighters.

Squamous cancers of the bladder are associated with chronic bladder infection by Schistosoma haematobium.

Cigarette smoking is known to increase, 2-6-fold, the risk of developing bladder cancer.

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