Introduction

The development of methods to safely preserve organs retrieved from victims of life-ending accidents greatly improved the versatility of human organ transplantation. In fact, the development of organ preservation is one of the cornerstones on which organ transplantation is built. Safe methods for organ preservation meant that organs thousands of miles from the recipient could be used for transplantation. Preservation also provided the time needed to identify the right recipient based on immunological tissue matching, size of organ and urgency of need for the transplant. Thousands of organs have been successfully transplanted, transforming the prospects of patients with end-stage organ diseases from one of potential death or serious morbidity to practically normal, useful and fulfilling lives. This great medical revolution is due not only to the availability of safe organ preservation methods, but also to the development of innovative surgical techniques and immunosuppression methods. All of this enormous success is directly attributed to the concerted efforts of research scientists exploring and solving problems related to human medicine with animal experimentation. Clearly, the role of organ preservation in clinical organ transplantation is and continues to be of great importance.

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