The increasing demand for transplantable organs is a major challenge. As pressures to expand the donor pool continue, we will be faced with donors with additional medical problems that might impact upon donor management. Numerous studies have defined donor age as an independent risk factor in determining outcomes. Are organs from older donors or those donors with comorbid medical conditions less tolerant to hypotension and ischemia, reperfusion injury and prolonged cold storage? Should procedures for organ recovery be altered based upon these variables? The answers to these questions and many more must be forthcoming as we attempt to maximize organ retrieval and maintain and improve our current patient and graft survival.
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