Further reading

Identification of stem cells and colony assays

Bradley TR, Metcalf D. (1966) The growth of mouse bone marrow cells in vitro. Australian Journal of Experimental Biology and Medical Science, 44, 287-299.

Curry JL, Trentin JJ. (1967) Hemopoietic spleen colony studies. I. Growth and differentiation. Developmental Biology, 15, 395-413.

Ichikawa Y, Pluznik DH, Sachs L. (1966) In vitro control of the development of macrophage and granulocyte colonies. Proceedings of the National Academy of Sciences of the United States of America, 56, 488-495.

Metcalf D. (1984) The Hematopoietic Colony Stimulating Factors. Amsterdam: Elsevier.

Till J, McCulloch E. (1961) A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. Radiation Research, 14, 213-222.

Stem cell plasticity

Brazelton TR, Rossi FM, Keshet GI et al. (2000) From marrow to brain: expression of neuronal phenotypes in adult mice. Science, 290, 1775-1779.

Camargo FD, Green R, Capetenaki Y et al. (2003) Single hematopoietic stem cells generate skeletal muscle through myeloid intermediates. Nature Medicine, 9(12), 1520-1527.

Ferrari G, Cusella-De Angelis G, Coletta M et al. (1998) Muscle regeneration by bone marrow-derived myogenic progenitors. Science, 279, 1528-1530.

Gussoni E, Soneoka Y, Strickland CD et al. (1999) Dystrophin expression in the mdx mouse restored by stem cell transplantation. Nature, 401, 390-394.

Lagasse E, Connors H, Al-Dhalimy M et al. (2000) Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nature Medicine, 6, 1229-1234.

Mezey E, Chandross KJ, Harta G et al. (2000) Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow. Science, 290, 1779-1782.

Orlic D, Kajstura J, Chimenti S et al. (2001) Bone marrow cells regenerate infarcted myocardium. Nature, 410, 701-705.

Wagers AJ, Sherwood RI, Christensen JL et al. (2002) Little evidence for developmental plasticity of adult hematopoietic stem cells. Science, 297, 2256-2259.

Wang X, Willenbring H, Akkari Y et al. (2003) Cell fusion is the principle source of bone-marrow-derived hepatocytes. Nature, 422, 897-901.

Molecular regulators of hematopoiesis

Cheng T, Rodrigues N, Dombkowski D et al. (2000) Stem cell repopulation efficiency but not pool size is governed by p27(kip1). Nature Medicine, 6, 1235-1240.

Cheng T, Rodrigues N, Shen H et al. (2000) Hematopoietic stem cell quiescence maintained by p21cip1/waf1. Science, 287, 1804-1808.

Kuhn R, Schwenk F, Aguet M et al. (1995) Inducible gene targeting in mice. Science, 269, 1427-1429.

Orkin SH. (1996) Development of the hematopoietic system. Current Opinion in Genetics and Development, 6, 597-602.

Reya T, Duncan AW, Ailles L et al. (2003) A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature, 423, 409-414.

Shivdasani RA, Orkin SH. (1996) The transcriptional control of hematopoiesis. Blood, 87, 4025-4039.

Shivdasani RA, Mayer EL, Orkin SH. (1995) Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL. Nature, 373, 432-434.

Homing and engraftment

Cashman JD, Lapidot T, Wang JC et al. (1997) Kinetic evidence of the regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow transplanted into immunodeficient mice. Blood, 89, 4307-4316.

Peled A, Petit I, Kollet O et al. (1999) Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4. Science, 283, 845-848.

Wright DE, Wagers AJ, Gulati AP et al. (2001) Physiological migration of hematopoietic stem and progenitor cells. Science, 294, 1933-1936.

Isolation of stem cells

Baum CM, Weissman IL, Tsukamoto AS et al. (1992) Isolation of a candidate human hematopoietic stem-cell population. Proceedings of the National Academy of Sciences of the United States of America, 89, 2804-2808.

Goodell MA, Brose K, Paradis G et al. (1996) Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. Journal of Experimental Medicine, 183(4), 1797-1806.

Spangrude GJ, Heimfeld S, Weissman IL. (1988) Purification and characterization of mouse hematopoietic stem cells. Science, 241, 58-62.

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