Further reading

Sinclair PB, Green AR, Grace C et al. (1997) Improved sensitivity of BCR-ABL detection: a triple-probe three-color fluorescence in situ hybridization system. Blood, 90, 1395-1402.

Speicher MR, Gwyn Ballard S, Ward DC. (1996) Karyotyping human chromosomes by combinatorial multi-fluor FISH. Nature Genetics, 12, 368-375.

Suijkerbuijk RF, Matthopoulos D, Kearney L et al. (1992) Fluorescent in situ identification of human marker chromosomes using flow sorting and Alu element-mediated PCR. Genomics, 13, 355-362.

Takashima T, Itoh M, Ueda Y et al. (1997) Detection of 14q32.33 translocation and t(11;14) in interphase nuclei of chronic B-cell leukemia/ lymphomas by in situ hybridization. International Journal of Cancer, 72, 31-38.

Telenius H, Pelmear AH, Tunnacliffe A et al. (1992) Cytogenetic analysis by chromosome painting using DOP-PCR amplified flow-sorted chromosomes. Genes, Chromosomes and Cancer, 4, 257-263.

Ueda Y, Nishida K, Miki T et al. (1997) Interphase detection of BCL6/IgH fusion gene in non-Hodgkin lymphoma by fluorescence in situ hybridization. Cancer Genetics and Cytogenetics, 99, 102-107.

Van Limbergen H, Poppe B, Michaux L et al. (2002) Identification of cytogenetic subclasses and recurring chromosomal aberrations in AML and MDS with complex karyotypes using M-FISH. Genes, Chromosomes & Cancer, 33, 60-72.

Veldman T, Vignon C, Schrock E et al. (1997) Hidden chromosome abnormalities in haematological malignancies detected by multicolour spectral karyotyping. Nature Genetics, 15, 406-410.

von Bergh A, Emanuel B, van Zelderen-Bhola S et al. (2000) A DNA probe combination for improved detection of MLL/11q23 breakpoints by double-color interphase-FISH in acute leukemias. Genes, Chromosomes & Cancer, 28, 14-22.

Comparative genomic hybridization and array CGH

Avet-Loiseau H, Andree-Ashley LE, Moore D et al. (1997) Molecular cytogenetic abnormalities in multiple myeloma and plasma cell leukemia measured using comparative genomic hybridization. Genes, Chromosomes & Cancer, 19, 124-133.

Avet-Loiseau H, Vigier M, Moreau A et al. (1997) Comparative genomic hybridization detects genomic abnormalities in 80% of follicular lymphomas. British Journal of Haematology, 97, 119-122.

Barth TFE, Dohner H, Werner CA et al. (1998) Characteristic pattern of chromosomal gains and losses in primary large B-cell lymphomas of the gastrointestinal tract. Blood, 91, 4321-4330.

Bentz M, Plesch A, Stilgenbauer S et al. (1998) Minimal sizes of deletions detected by comparative genomic hybridization. Genes, Chromosomes & Cancer, 21, 172-175.

Cai WW, Mao JH, Chow CW et al. (2002) Genome-wide detection of chromosomal imbalances in tumors using BAC microarrays. Nature Biotechnology, 20, 393-396.

Carter NP, Fiegler H, Piper J. (2002) Comparative analysis of comparative genomic hybridization microarray technologies: report of a workshop sponsored by the Wellcome Trust. Cytometry, 49, 43-48.

Cigudosa JC, Rao PH, Calasanz MJ et al. (1998) Characterization of nonrandom chromosomal gains and losses in multiple myeloma by comparative genomic hybridization. Blood, 91, 3007-3010.

El-Rifai W, Elonen E, Larramendy M et al. (1997) Chromosomal breakpoints and changes in DNA copy number in refractory acute myeloid leukemia. Leukemia, 11, 958-963.

Forozan F, Karhu R, Kononen J et al. (1997) Genome screening by comparative genomic hybridization. Trends in Genetics, 13, 405-409.

Haas O, Henn T, Romanakis K et al. (1998) Comparative genomic hybridization as part of a new diagnostic strategy in childhood hyper-diploid acute lymphoblastic leukemia. Leukemia, 12, 474-481.

Houldsworth J, Mathew S, Rao PH et al. (1996) REL proto-oncogene is frequently amplified in extranodal diffuse large cell lymphoma. Blood, 87, 25-29.

Joos S, Otano-Joos MI, Ziegler S et al. (1996) Primary mediastinal (thymic) B-cell lymphoma is characterized by gains of chromosomal material including 9p and amplification of the REL gene. Blood, 87, 1571-1578.

Kallioniemi A, Kallioniemi OP, Sudar D et al. (1992) Comparative ge-nomic hybridization for molecular cytogenetic analysis of solid tumors. Science, 258, 818-821.

Karhu R, Knuutila S, Kallioniemi OP et al. (1997) Frequent loss of the 11q14-24 region in chronic lymphocytic leukemia: a study by comparative genomic hybridization. Tampere CLL Group. Genes, Chromosomes and Cancer, 19, 286-290.

Karhu R, Siitonen S, Tanner M et al. (1997) Genetic aberrations in pediatric acute lymphoblastic leukemia by comparative genomic hybridization. Cancer Genetics and Cytogenetics, 95, 123-129.

Monni O, Oinonen R, Elonen E et al. (1998) Gain of 3q and deletion of 11q22 are frequent aberrations in mantle cell lymphoma. Genes, Chromosomes & Cancer, 21, 298-307.

Paszek-Vigier M, Talmant P, Mechinaud F et al. (1997) Comparative genomic hybridization is a powerful tool, complementary to cy-togenetics, to identify chromosomal abnormalities in childhood acute lymphoblastic leukaemia. British Journal of Haematology, 99, 589-596.

Rao PH, Houldsworth J, Dyomina K et al. (1998) Chromosomal and gene amplification in diffuse large B-cell lymphoma. Blood, 92, 234-240.

Solinas-Toldo S, Lampel S, Stilgenbauer S et al. (1997) Matrix-based comparative genomic hybridization: biochips to screen for genomic imbalances. Genes, Chromosomes & Cancer, 20, 399-407.

Wessendorf S, Schwaenen C, Kohlhammer H et al. (2003) Hidden gene amplifications in aggressive B-cell non-Hodgkin lymphomas detected by microarray-based comparative genomic hybridization.

Oncogene, 22, 1425-1429.

Expression profiling

Armstrong SA, Staunton JE, Silverman LB et al. (2002) MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia. Nature Genetics, 30, 41-47.

Debernardi S, Lillington DM, Chaplin T et al. (2003) Genome-wide analysis of acute myeloid leukemia with normal karyotype reveal a unique pattern of homeobox gene expression distinct from those with translocation-mediated fusion events. Genes, Chromosomes & Cancer, 37, 149-158.

Golub TR. (2001) Genomic approaches to the pathogenesis of hematologic malignancy. Current Opinion in Hematology, 8, 252-261.

Golub TR. (2001) Genome-wide views of cancer. New England Journal of Medicine, 344, 601-602.

Golub TR, Slonim DK, Tamayo P et al. (1999) Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science, 286, 531-537.

Schoch C, Kohlmann A, Schnittger S et al. (2002) Acute myeloid leuke-mias with reciprocal rearrangements can be distinguished by specific gene expression profiles. Proceedings of the National Academy of Sciences of the United States of America, 99,10008-10013.

Shipp MA, Ross KN, Tamayo P et al. (2002) Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning. Nature Medicine, 8, 68-74.

Tamayo P, Slonim D, Mesirov J et al. (1999) Interpreting patterns of gene expression with self-organizing maps: methods and application to hematopoietic differentiation. Proceedings of the National Academy of Sciences of the United States of America, 96, 2907-2912.

Yeang CH, Ramaswamy S, Tamayo P et al. (2001) Molecular classification of multiple tumor types. Bioinformatics, 17, S316-S322.

Yeoh EJ, Ross ME, Shurtleff SA et al. (2002) Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling. Cancer Cell, 1, 133-143.

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