Transport Pathway Of Nanoparticles

Ocular transport of polybutylcyanoacrylate nanoparticles has been studied by Zimmer et al. (54) using fluoroscence microscopy. Nanoparticles were labeled with rhodamine 6G or propidium iodide as fluorescent dyes and

time !

Fig. 2 Adsorption isotherms of betaxolol chlorhydrate. Betaxolol solution; suspension A; suspension B; suspension C. (From Ref. 80.)

Fig. 2 Adsorption isotherms of betaxolol chlorhydrate. Betaxolol solution; suspension A; suspension B; suspension C. (From Ref. 80.)

Table 1 Physicochemical Characteristics1 of Polyalkylcyanoacrylate Nanoparticles

Adsorption

Size (nm) Zeta-potential percentage (S.D.) (mV) (S.D.) (S.D.)

Suspension A

Adsorption

Size (nm) Zeta-potential percentage (S.D.) (mV) (S.D.) (S.D.)

Suspension A

without betaxolol chl.

246 (3.6)

-15(1)

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