I

0.001—1—'—1—1—1■—1—1—1—1—1—'—■—' •10 0 10 20 30 40 50 60 TIME (DAYS)

Figure 4 Relationship between aqueous humor ascorbate concentrations and recovery period in rabbits with intraocular microdialysis probes placed into the anterior or posterior chamber of the eye. Area between dashed lines represents reported steady-state aqueous humor ascorbate concentrations.

were used for aqueous sampling. For the implantation of the probe in the vitreous, a 22 gauge needle was inserted into the eye about 3 mm below the corneal-scleral limbus through the pars plana. The needle was then removed and the probe adjusted such that the membrane was in the mid-

Figure 5 Relationship between basal ascorbate blood aqueous transport versus recovery period in rabbits with intraocular microdialysis probes in the anterior and posterior chambers. Dashed line represents theoretical basal transport. (Bars represent ± SD).

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