Tumour necrosis factors

The TNF family of cytokines essentially consists of two related regulatory factors: TNF-a (cachectin) and TNF-P (lymphotoxin). Although both molecules bind the same receptor and induce very similar biological activities, they display limited sequence homology. The human TNF-a and -P genes are located adjacent to each other on chromosome 6, being separated by only 1100 base pairs. Both contain three introns, and their expression appears to be coordinately regulated. TNF-a, sometimes referred to simply as TNF, has been studied in significantly greater detail than lymphotoxin.

Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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