Sources of biopharmaceuticals

The bulk of biopharmaceuticals currently on the market are produced by genetic engineering using various recombinant expression systems. Although a wide range of potential protein production systems are available (Table 5.1), most of the recombinant proteins that have gained marketing approval to date are produced either in recombinant E. coli or in recombinant mammalian cell lines (Table 5.2). Such recombinant systems are invariably constructed by the introduction of a gene or cDNA coding for the protein of interest into a well-characterized strain of the chosen producer cell (Chapter 3). Examples include E. coli K12 and CHO strain K1 (CHO-K1). Each recombinant production system displays its own unique set of advantages and disadvantages, as described below.

Supplements For Diabetics

Supplements For Diabetics

All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.

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