Introduction

All pharmaceutical finished products undergo rigorous QC testing in order to confirm their conformance to predetermined specifications. Potency testing is of obvious importance, ensuring that the drug will be efficacious when administered to the patient. A prominent aspect of safety testing entails analysis of product for the presence of various potential contaminants.

The range and complexity of analytical testing undertaken for recombinant biopharmaceu-ticals far outweighs that undertaken with regard to 'traditional' pharmaceuticals manufactured by organic synthesis. Not only are proteins (or additional biopharmaceuticals such as nucleic acids; Chapter 14) much larger and more structurally complex than traditional low molecular mass drugs, their production in biological systems renders the range of potential contaminants far broader (Table 7.1). Recent advances in analytical techniques render practical the routine analysis of complex biopharmaceutical products. An overview of the range of finished-product tests of recombinant protein biopharmaceuticals is outlined below. Explanation of the theoretical basis underpinning these analytical methodologies is not undertaken, as this would considerably broaden the scope of the text. Appropriate references are provided at the end of the chapter for the interested reader.

Supplements For Diabetics

Supplements For Diabetics

All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.

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