Blood plays various vital roles within the body and it is not surprising that a number of processes have evolved capable of effectively maintaining haemostasis (the rapid arrest of blood loss upon vascular damage, in order to maintain a relatively constant blood volume). In humans, three main mechanisms underline the haemostatic process:

• The congregation and clumping of blood platelets at the site of vascular injury, thus effectively plugging the site of blood leakage.

• Localized constriction of the blood vessel, which minimizes further blood flow through the area.

• Induction of the blood coagulation cascade. This culminates in the conversion of a soluble serum protein, fibrinogen, into insoluble fibrin. Fibrin monomers then aggregate at the site of

Pharmaceutical biotechnology: concepts and applications Gary Walsh © 2007 John Wiley & Sons, Ltd ISBN 978 0 470 01244 4 (HB) 978 0 470 01245 1 (PB)

damage, thus forming a clot (thrombus) to seal it off. These mechanisms are effective in dealing with small vessel injuries (e.g. capillaries and arterioles), although they are ineffective when the damage relates to large veins/arteries.

Supplements For Diabetics

Supplements For Diabetics

All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.

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