Further reading Books

Buxbaum, E. 2006. Fundamentals of Protein Structure and Function. Springer. Carey, P. 1996. Protein Engineering and Design. Academic Press.

Cavanagh, J., Fairbrother, W.J., Palmer III, A.G., Skelton, N.J., and Rance, M. 2006. Protein NMR Spectroscopy:

Principles and Practice, 2nd edition. Academic Press. Creighton, T. 2006. Proteins. Oxford University Press.

Eidhammer, I., Jonassen, I., and Taylor, W.R. 2006. Protein Bioinformatics. Wiley.

Fersht, A. 1999. Structure and Mechanism in Protein Science. Freeman.

Higgins, D. 2000. Bioinformatics. Oxford University Press.

Rehm, H. 2006. Protein Biochemistry and Proteomics. Academic Press.

Walsh, C. 2005. Posttranslational Modification of Proteins. Roberts & Company Publishers.


Protein structure and folding

Al-Lazikani, B., Jung, J., Xiang, Z., and Honig, B. 2001. Protein structure prediction. Current Opinion in Chemical Biology 5(1), 51-56.

Basharov, M. 2003. Protein folding. Journal of Cellular and Molecular Medicine 7(3), 223-237.

Bonvin, A.M., Boelens, R., and Kaptein, R. 2005. NMR analysis of protein interactions. Current Opinion in Chemical Biology 9(5), 501-508.

Brannigan, J. and Wilkinson, A. 2002. Protein engineering 20 years on. Nature Reviews: Molecular Cell Biology 3(12), 964-970.

Chasse, G.A., Rodriguez, A.M., Mak, M.L., Deretey, E., Perczel, A., Sosa, C.P., Enriz, R.D., and Csizmadia I.G. 2001. Peptide and protein folding. Journal of Molecular Structure: Theochem 537, 319-361.

Fiser, A. 2004. Protein structure modeling in the proteomics era. Expert Review of Proteomics 1(1), 97-110.

Floudas, C.A., Fung, H.K., McAllister, S.R., Monnigmann, M., and Rajgaria, R. 2006. Advances in protein structure prediction and de novo protein design: a review. Chemical Engineering Science 61(3), 966-988.

Gustafsson, C., Govindarajan S., and Minshull, J. 2003. Putting engineering back into protein engineering: bioinformatics approaches to catalyst design. Current Opinion in Biotechnology 14(4), 366-370.

Koing, S. 2005. Functional protein analysis using mass spectrometry. Current Organic Chemistry 9(9), 875-887.

Osguthorpe, D. 2000. Ab initio protein folding. Current Opinion in Structural Biology 10(2), 146-152.

Petrey, D. and Honig, B. 2005. Protein structure prediction: inroads to biology. Molecular Cell 20(6), 811-819.

Radford, S. 2000. Protein folding; progress made and promises ahead. Trends in Biochemical Sciences 25(12), 611-618.

Wishart, D. 2005. NMR spectroscopy and protein structure determination: applications to drug discovery and development. Current Pharmaceutical Biotechnology 6(2), 105-120.

Protein stability and post-translational modifications

Bayle, J.H. and Crabtree, G.R. 1997. Protein acetylation; more than chromatin modification to regulate transcription. Chemistry and Biology 4(12), 885-888.

Bosshard, H.R., Marti, D.N., and Jelesarov, I. 2004. Protein stabilization by salt bridges: concepts, experimental approaches and clarification of some misunderstandings. Journal of Molecular Recognition 17(1), 1-16.

Chi, E.Y., Krishnan, S., Randolph, T.W., and Carpenter, J.F. 2003. Physical stability of proteins in aqueous solution: mechanism and driving forces in nonnative protein aggregation. Pharmaceutical Research 20(9), 1325-1336.

Frokjaer, S and Otzen, D. 2005. Protein drug stability: a formulation challenge. Nature Reviews: Drug Discovery 4(4), 298-306.

Imperiali, B. and O'Connor, S. 1999. Effect of N-linked glycosylation on glycopeptide and glycoprotein structure. Current Opinion in Chemical Biology 3(6), 643-649.

Lee, B. and Vasmatis, G. 1997. Stabilization of protein structures. Current Opinion in Biotechnology 8, 423-428.

McLihnney, R. 1990. The fats of life; the importance and function of protein acylation. Trends in Biochemical Sciences 15, 387-391.

Merry, T. 1999. Current techniques in protein glycosylation analysis - a guide to their application. Acta Bio-chimica Polonica 46(2), 303-314.

Parodi, A. 2000. Protein glycosylation and its role in protein folding. Annual Review of Biochemistry 69, 69-93.

Van den Burg, B. and Eijsink, V. 2002. Selection of mutations for increased protein stability. Current Opinion in Biotechnology 13(4), 333-337.

Walsh, G. and Jefferis, R. 2006. Posttranslational modifications in the context of therapeutic proteins. Nature Biotechnology 24, 1241-1252.

Yan, J.X., Packer, N.H., Gooley, A.A., and Williams, K.L. 1998. Protein phosphorylation; technologies for the identification of phosphoamino acids. Journal of Chromatography A 808(1-2), 23-41.

Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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