Erythropoietin and thrombopoietin

Basser, R. 2002. The impact of thrombopoietin on clinical practice. Current Pharmaceutical Design 8(5), 369-377.

Bottomley, A., Thomas, R., van Steen, K., Flechtner, H., Djulbegovic, B. 2002. Human recombinant erythropoietin and quality of life: a wonder drug or something to wonder about? Lancet Oncology 3(3), 145-153.

Buemi, M., Aloisi, C., Cavallaro, E., Corica, F., Floccari, F., Grasso, G., Lasco, A., Pettinato, G, Ruello, A., Sturiale, A., and Frisina, N. 2002. Recombinant human erythropoietin: more than just the correction of uremic anemia. Journal of Nephrology 15(2), 97-103.

Corwin, H. 2006. The role of erythropoietin therapy in the critically ill. Transfusion Medicine Reviews 20(1), 27-33.

Engert, A. 2005. Recombinant human erythropoietin in oncology: current status and further developments. Annals of Oncology 16 (10), 1584-1595.

Fried, W. 1995. Erythropoietin. Annual Review of Nutrition 15, 353-377.

Geddis, A.E., Linden, H.M., and Kaushansky, K. 2002. Thrombopoietin: a pan-hematopoietic cytokine. Cytokine and Growth Factor Reviews 13(1), 61-73.

Heuser, M. and Ganser, A. 2006. Recombinant human erythropoietin in the treatment of nonrenal anemia. Annals of Hematology 85(2), 69-78.

Kaushansky, K. 1997. Thrombopoietin - understanding and manipulating platelet production. Annual Review of Medicine 48, 1-11.

Kaushansky, K. and Drachman, J. 2002. The molecular and cellular biology of thrombopoietin: the primary regulator of platelet production. Oncogene 21(21), 3359-3367.

Kaushansky, K. 2005. The molecular mechanisms that control thrombopoiesis. Journal of Clinical Investigation 115(12), 3339-3347.

Kendall, R. 2001. Erythropoietin. Clinical and Laboratory Haematology 23(2), 71-80.

Lok, S., Kaushansky, K., Holly, R.D., Kuijper, J.L., Lofton-Day, C.E., Oort, P.J., Grant, F.J., Heipel, M.D., Burkhead, S.K., Kramer, J.M., Bell, L.A., Sprecher, C.A., Blumberg, H., Johnson, R., Prunkard, D., Ching, A.F.T., Mathewes, S.L., Bailey, M.C., Forstrom, J.W., Buddle, M.M., Osborn, S.G., Evans, S.J., Sheppard, P.O.,

Presnell, S.R., O'Hara, P.J., Hagen, F.S., Roth, G.J., and Foster, D.C. 1994. Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo. Nature 369, 565-568.

Markham, A. and Bryson, H. 1995. Epoetin alfa, a review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in non-renal applications. Drugs 49(2), 232-254.

Miyazaki, H. and Kato, T. 1999. Thrombopoietin: biology and clinical potential. International Journal of Haematology 70(4), 216-225.

Ogden, J. 1994. Thrombopoietin - the erythropoietin of platelets? Trends in Biotechnology 12, 389-390.

Strauss, R. 2006. Controversies in the management of the anemia of prematurity using single-donor red blood cell transfusions and/or recombinant human erythropoietin. Transfusion Medicine Review 20(1), 34-44.

Colony-stimulating factors

Duarte, R. and Frank, D. 2002. The synergy between stem cell factor (SCF) and granulocyte colony stimulating factor (G-CSF): molecular basis and clinical relevance. Leukaemia and Lymphoma 43(6), 1179-1187.

Esser, M. and Brunner, H. 2003. Economic evaluations of granulocyte colony stimulating factor in the prevention and treatment of chemotherapy-induced neutropenia. Pharmacoeconomics 21(18), 1295-1313.

Fleetwood, A.J., Cook, A.D., and Hamilton, J.A. 2005. Functions of granulocyte-macrophage colony stimulating factor. Critical Reviews in Immunology 25(5), 405-428.

Frampton, J.E., Lee, C.R., and Faulds, D. 1994. Filgrastim. A review of its pharmacological properties and therapeutic efficacy in neutropenia. Drugs 48(5), 731-760.

Frampton, J.E., Yarker, Y.E., and Goa, K.L. 1995. Lenograstim. A review of its pharmacological properties and therapeutic efficacy in neutropenia and related clinical settings. Drugs 49(5), 767-793.

Hamilton, J. 1997. CSF-1 signal transduction. Journal of Leukocyte Biology 62 (2), 145-155.

Harousseau, J. 1997. The role of colony-stimulating factors in the treatment of acute leukaemia. Biodrugs 7(6), 448-460.

Heuser, M. and Ganser, A. 2005. Colony stimulating factors in the management of neutropenia and its complications. Annals of Hematology 84(11), 697-708.

Lyman, G. and Kuderer, N. 2004. The economics of the colony stimulating factors in the prevention and treatment of febrile neutropenia. Critical Review in Oncology and Hematology 50(2), 129-146.

Tabbara, I.A., Ghazal, C.D., and Ghazal, H.H. 1996. The clinical applications of granulocyte-colony-stimulating factor in haematopoietic stem cell transplantation: a review. Anticancer Research 16 (6B), 3901-3905.

Watowich, S.S., Wu, H., Socolovsky, M., Klingmuller, U., Constantinescu, S.N., and Lodish, H.F. 1996. Cytokine receptor signal transduction and the control of haematopoietic cell development. Annual Review of Cell and Developmental Biology 12, 91-128.

Insulin-like growth factors

Bach, L. 1999. The insulin-like growth factor system: basic and clinical aspects. Australian and New Zealand

Journal of Medicine. 29(3), 355-361. Furstenberger, G. and Senn, H. 2002. Insulin like growth factors and cancer. Lancet Oncology, 3(5), 298-302. Kostecka, Z. and Blahovec, J. 2002. Animal insulin-like growth factor binding proteins and their biological functions. Veterinarni Medicina 47(2-3), 75-84. LeRoith, D. 1997. Insulin-like growth factors. New England Journal of Medicine 336(9), 633-640. Schmid, C. 1995. Insulin-like growth factors. Cell Biology International 19(5), 445-457. Yee, D. 2006. Targeting insulin-like growth factor pathways. British Journal of Cancer 94(4), 465-468. Zumkeller, W. 2002. The insulin-like growth factor system in hematopoietic cells. Leukaemia and Lymphoma 43(3), 487-491.

Epidermal growth factor and platelet-derived growth factor

Board, R. and Jayson, G. 2005. Platelet-derived growth factor receptor (PDGFR): a target for anti cancer therapeutics. Drug Resistance Updates 8(1-2), 75-83.

Boonstra, J., Rijken, P., Humbel, B., Cremers, F., Verkleij, A., and van Bergen en Henegouwen, P. 1995. The epidermal growth factor. Cell Biology International 19(5), 413-430.

Johnstone, P. 2002. The epidermal growth factor receptor: a new target for anticancer therapy - introduction. Current Problems in Cancer 26(3), 114-164.

Kane, S. 2006. Cancer therapies targeted to the epidermal growth factor receptor and its family members. Expert Opinion on Therapeutic Patents 16 (2), 147-164.

Leserer, M., Gschwind, A., and Ullrich, A. 2000. Epidermal growth factor receptor signal transactivation. IUBMB Life 49(5), 405-430.

Shih, A. and Holland, E. 2006. Platelet-derived growth factor (PDGF) and glial tumorigenesis. Cancer Letters 232(2), 139-147.

Wakeling, A. 2002. Epidermal growth factor receptor tyrosine kinase inhibitors. Current Opinion in Pharmacology 2(4), 382-387.

Fibroblast growth factor/transforming growth factor

Dennler, S., Goumans, M.J., and ten Dijke, P. 2002. Transforming growth factor beta signal transduction. Journal of Leukocyte Biology 71(5), 731-740. Hu, X. and Zuckerman, K. 2001. Transforming growth factor: signal transduction pathways, cell cycle mediation, and effects on hematopoiesis. Journal of Hematotherapy and Stem Cell Research 10(1), 67-74. Imel, E. and Econs, M. 2005. Fibroblast growth factor 23: roles in health and disease. Journal of the American

Society of Nephrology 16(9), 2565-2575. Kim, I.Y., Kim, M.M., and Kim, S.J. 2005. Transforming growth factor beta: biology and clinical relevance.

Journal of Biochemistry and Molecular Biology 38(1), 1-8. Le, Y., Yu, X., Ruan, L., Wang, O., Qi, D., Zhu, J., Lu, X., Kong, Y., Cai, K., Pang, S., Shi, X., and Wang, J.M. 2005. The immunopharmacological properties of transforming growth factor beta. International Immunopharmacology 9(13-14), 1771-1782. Narayan, S., Thangasamy, T., and Balusu, R. 2005. Transforming growth factor beta receptor signaling in cancer.

Frontiers in Bioscience 10, 1135-1145. Powers, C.J., McLeskey, S.W., and Wellstein, A. 2000. Fibroblast growth factors, their receptors and signalling. Endocrine Related Cancer 7(3), 165-197.

Neurotrophic and related factors

Allen, S. and Dawbarn, D. 2006. Clinical relevance of the neurotropins and their receptors. Clinical Science 110(2), 175-191.

Butte, M. 2001. Neurotrophic factor structure reveals clues to evolution, binding, specificity and receptor activation. Cellular and Molecular Life Sciences 58(8), 1003-1013.

Chao, M.V., Rajagopal, R., and Lee, F.S. 2006. Neurotrophin signaling in health and disease. Clinical Science 110(2), 167-173.

Fu, S. and Gordon, T. 1997. The cellular and molecular basis of peripheral nerve regeneration. Molecular Neurobiology 14, 67-116.

Haque, N.S.K., Borghesani, P., and Isacson, O. 1997. Therapeutic strategies for Huntington's disease, based on a molecular understanding of the disorder. Molecular Medicine Today 3(4), 175-183.

Hefti, F. 1997. Pharmacology of neurotrophic factors. Annual Review of Pharmacology and Toxicology 37, 239-267.

Kwon, Y. 2002. Effect of neurotrophic factors on neuronal stem cell death. Journal of Biochemistry and Molecular Biology 35(1), 87-93.

Sofroniew, M.V., Howe, C.L., and Mobley, W.C. 2001. Nerve growth factor signalling, neuroprotection and neural repair. Annual Review of Neuroscience 24, 1217-1281.

Yamada, K., Mizuno, M., and Nabeshima, T. 2002. Role for brain-derived neurotrophic factor in learning and memory. Life Sciences 70 (7), 735-744.

Thorne, R. and Frey, W. 2001. Delivery of neurotrophic factors to the central nervous system - pharmacokinetic considerations. Clinical Pharmacokinetics 40(12), 907-946.

Tatagiba, M., Brosamle, C., and Schwab, M.E. 1997. Regeneration of injured axons in the adult mammalian central nervous system. Neurosurgery 40(3), 541-546.

Walsh, G. 1995. Nervous excitement over neurotrophic factors. Bio/Technology 13, 1167-1171.

Yamada, M., Ikeuchi, T., and Hatanaka, H. 1997. The neurotrophic action and signalling of epidermal growth factor. Progress in Neurobiology 51(1), 19-37.

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