Solutions To Exercises Lesson

1. b A substance used to prevent, diagnose, or treat disease or to prevent pregnancy. (para 3-2a)

2. c The science of poisons. (para 3-2e)

4. b To relieve the symptoms of a disease or condition. (para 3-4c)

5. c The weak patient may require smaller doses of a drug to achieve an effect.

6. b Drug dependence is said to occur when the patient has either a physiological or psychological need for a drug. (para 3-6)

7. b Synergism occurs when the combined effect of two drugs is greater than the sum of their independent effects. (para 3-5j(1))

9. c In this route of administration the drug is absorbed without passing through the gastrointestinal tract. (para 3-5k(2))

10. b Since body membranes are lipid in nature, a drug that will pass through lipid material will be absorbed much more quickly than ionized drug particles. (para 3-9b)

11. b The metabolic process of changing a drug. (para 3-11)

12. c The process of eliminating a drug or its metabolites from the body.

13. b A drug (the key) combines with a receptor-site (the lock) to produce a pharmacological effect. (para 3-14a)

14. c Passive transport occurs when molecules of a drug move from an area of high concentration to an area of low concentration, while active transport occurs when a "carrier molecule" carries a drug molecule across a cell membrane. (para 3-9c(1) and (2))

15. a Drugs that are similar in composition and structure may have similar effects.

16. a Competitive antagonists combine with the receptor-site and prevent another drug from combining with the receptor-site, while physiological antagonists reverse the action of a drug by acting on a different receptor-site to cause a different physiological reaction. (para 3-14c(1) and (2))

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