a. Most people undergo changes in mood. You can probably remember when you have been "up" (that is, right before a three-day weekend) and when you have been "down" (that is, right after a three-day weekend). Physicians have found antidepressant agents to be useful in the treatment of depression, which is not time limited and causes the patient social and economic difficulties.
b. Depression can be caused by chemical imbalances in the body, by stress, and by situations in the environment. It has been found that psychotherapy, reduction of stress, and improvement in the environment can be successful in treating some types of depression. However, in depression that results from chemical imbalances in the body, these types of treatment have not proven to be very effective.
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