EHydroxyzine Hydrochloride Atarax or Hydroxyzine Pamoate Vistaril

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(1) Uses. Hydroxyzine has the following three primary uses:

(a) Antianxiety agent. The drug is used to treat anxiety, tension, and agitation.

(b) Antiemetic agent. Because hydroxyzine does have some antiemetic (antinausea and vomiting) properties, it is used in its injectable form (hydroxyzine pamoate) to manage postoperative nausea and vomiting.

(c) Antipruritic agent. Hydroxyzine has been used because of its antipruritic (anti-itch) properties.

NOTE: Atarax® is sometimes used as a sedative.

(2) Adverse effects. There is an extremely low incidence of adverse reactions with this drug. Some drowsiness may occur during the initial days of therapy; however, this drowsiness is short-lived.

(3) Cautions and warnings. An individual taking hydroxyzine should be cautioned against drinking alcohol and taking other central nervous system depressants because of the additive effect that may be produced. Furthermore, persons taking this drug should be cautioned against operating machinery (for example, driving an automobile).

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